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### Abstract

In this letter, we report a case of a child having 4-year old nonhealing leg ulcers with a severe form of epidermolysis bullosa, successfully treated with a new product based on nano-biodegradable polysaccharide engineered to mimic heparan sulfates.

This simple treatment, applied twice a week, induced complete healing within a month and has lasted without recurrence for 2 years. Furthermore, the treatment resulted in a rapid pain relief, whereas standard treatments average of 2 hours daily dressing changes with no closure.

This product can bring a solution to this devastating and endless sufferance.